on (March 18, 2025) in the presence of the head of departments and lecturer a symposium entitled (8-Hydroxy-2'-deoxyguanosine (8-OHdG)), was presented by (Assist lect. Ava Hammdi Saeed) from the Medical Laboratory department , Where it has been explained about, 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a key marker of oxidative DNA damage, formed by reactive oxygen species oxidizing guanine. Its mutagenic potential, causing G-to-T transversions, links it to cancer, neurodegeneration, and aging. Detected via HPLC-MS, ELISA, or immunohistochemistry, 8-OHdG reflects oxidative stress and repair capacity. Though targeted by OGG1-mediated repair, persistent damage drives disease. It remains a vital research tool for connecting oxidative stress to health outcomes, At the end of the symposium 8-OHdG (8-hydroxy-2'-deoxyguanosine) is a biomarker of oxidative DNA damage, commonly used to assess oxidative stress in biological systems. Elevated levels of 8-OHdG are associated with various conditions, including aging, cancer, neurodegenerative diseases, and cardiovascular disorders. Measuring 8-OHdG in urine, blood, or tissues can provide insights into the impact of oxidative stress and the effectiveness of antioxidant interventions. However, while it is a useful marker, it should be interpreted alongside other oxidative stress indicators for a comprehensive assessment.